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MOA
Electron Transfer for Energy Production:
Acts as a redox cofactor in mitochondrial oxidative phosphorylation, accepting and donating electrons in the electron transport chain (ETC) to generate ATP.
PARP Enzyme Regulation:
Involved in the repair of single-strand DNA breaks via poly(ADP-ribose) polymerases (PARPs), protecting genome integrity under stress.
Neurotransmitter and Cognitive Modulation (nasal delivery specific):
Through olfactory and trigeminal pathways, NAD+ may directly influence dopamine, serotonin, and noradrenaline synthesis, modulating cognitive and mood-related pathways.
Sirtuin Activation:
Serves as a required substrate for sirtuins (SIRT1–SIRT7), a family of enzymes that regulate DNA repair, mitochondrial biogenesis, inflammation, and longevity genes.
CD38 and Immune Modulation:
CD38 consumes NAD+ and is upregulated in aging and inflammation. Increasing NAD+ may buffer age-related NAD+ depletion, reducing inflammatory immune signaling.
More Information
This product requires a good faith medical-screening. After purchasing, you will receive instructions to schedule and complete your intake screening before your order can be fulfilled. Each intake is valid for one calendar year.
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